Prof. Laura Fiorucci
Contact details
Professor of Biochemistry at the Faculty of Medicine
University of Rome Tor Vergata
Via Montpellier 1, 00133 Rome
Office: Department of Experimental Medicine and Biochemical Sciences
Tel: +39 06 72596478
Research Activity
Scientific topics: A. Proteases and inhibitors: mast cell proteases, structural and functional studies, interaction with endogenous inhibitors, search for new inhibitors;. B. Protein folding/unfolding of cytochrome c as probed by limited proteolysis, its interaction with lipids and search for the structural requirements for its pro-apoptotic activity.
Recent Publications
[1] Sinibaldi F, Fiorucci L, Patriarca A, Lauceri R, Ferri T, Coletta M, Santucci R. Insights into Cytochrome c-Cardiolipin Interaction. Role Played by Ionic Strength (2008) Biochemistry. [Epub ahead of print]
[2] Santucci R., Sinibaldi F., Fiorucci L. Protein Folding, Unfolding and Misfolding Role Played by Intermediate States Mini-Reviews in Medicinal Chemistry, 2008, 8, 000-000 1
[3]Agueci F., Polticelli F., Sinibaldi F., Piro M.C., Santucci R., Fiorucci L. (2007) Probing the effect of mutations on cytochrome c stability Protein and Peptide Letters, 14, 335-339 ISSN 0929-8665
[4]Sinibaldi F., Mei G., Ponticelli F., Piro M.C., Howes, B.D., Smulevich G., Santucci R., Ascoli F., Fiorucci L. (2005) ATP specifically driver refolding of non native conformations of cytochrome c Protein Science 14: 1049-1058 ISSN 0961-8368
[...] Prof. Laura FIORUCCI [...]